SB-410220


SMILES O=C(Nc1ccnc2c1c(F)ccc2F)Nc1ccc(cc1)N(C)C
InChIKey AZFKSWSBVCFBCG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 342.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 7.7 7.7 7.7 Guide to Pharmacology
OX1 OX1R Human Orexin A pKd 8.35 8.35 8.35 ChEMBL
OX1 OX1R Human Orexin A pKi 8.06 8.06 8.06 ChEMBL
OX2 OX2R Human Orexin A pKi 6.3 6.3 6.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database