CHEMBL306672


SMILES O=C1c2ccccc2C(=O)N1CCCCCN1CCN(c2cccc(Cl)c2Cl)CC1
InChIKey HZMBQYFOWZCHKD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 445.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.25 8.25 8.25 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.98 6.98 6.98 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.11 8.11 8.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.96 7.96 7.96 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.06 7.06 7.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database