CHEMBL263101
SMILES | Cc1nc2ncccc2cc1-c1ccc2cc(CCN3CCC[C@H]3C)ccc2n1 |
InChIKey | VLKAMDZYTNJHHG-QGZVFWFLSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 0 |
Rotatable bonds | 4 |
Molecular weight (Da) | 382.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Rat | Histamine | A | pKi | 8.45 | 8.64 | 8.71 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKi | 9.47 | 9.48 | 9.52 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Rat | Histamine | A | pEC50 | 8.14 | 8.14 | 8.14 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pEC50 | 8.8 | 8.8 | 8.8 | ChEMBL |