CHEMBL309118


SMILES O=C(NCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2c1-c1ccccc1C2=O
InChIKey CVJYJKRPDVXLEY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 493.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.82 6.82 6.82 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.4 5.4 5.4 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.44 7.44 7.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.29 6.29 6.29 ChEMBL
D3 DRD3 Rat Dopamine A pKi 7.37 7.37 7.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database