CHEMBL267265


SMILES N=C(N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@@H](N)CCCCC(=O)CCC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O
InChIKey KDTZLQMUHBEBMZ-OUBWENQOSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 11
Rotatable bonds 9
Molecular weight (Da) 879.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pKd 8.7 8.7 8.7 ChEMBL
MC3 MC3R Human Melanocortin A pKd 8.3 8.3 8.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pIC50 5.7 5.7 5.7 ChEMBL
MC5 MC5R Human Melanocortin A pIC50 7.77 7.77 7.77 ChEMBL
MC3 MC3R Human Melanocortin A pIC50 7.92 7.92 7.92 ChEMBL
MC4 MC4R Human Melanocortin A pIC50 6.52 6.52 6.52 ChEMBL