SKF-75670


SMILES CN1CCc2c(C(C1)c1ccccc1)cc(c(c2)O)O
InChIKey LIHCKGZEDBNUJG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 269.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 8.7 8.7 8.7 Guide to Pharmacology
D1 DRD1 Human Dopamine A pKi 8.06 8.06 8.06 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.72 5.72 5.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pEC50 9.35 9.35 9.35 ChEMBL