IOLOPRIDE


SMILES CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(I)c1O
InChIKey CANPFCFJURGKAX-JTQLQIEISA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 404.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 4.92 4.92 4.92 ChEMBL
D2 DRD2 Rat Dopamine A pKi 9.2 9.38 9.58 ChEMBL
D2 DRD2 Rat Dopamine A pKd 9.37 9.37 9.37 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.38 8.38 8.38 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.38 8.38 8.38 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.24 6.24 6.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 8.92 8.92 8.92 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 8.47 8.72 8.92 ChEMBL