CHEMBL268258


SMILES COc1cccc2c1CCC[C@H]2CN(C)CCc1ccc2ccoc2c1
InChIKey MHPMXTGKTXJIDI-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 349.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Dog Adrenoceptors A pKi 5.76 5.76 5.76 ChEMBL
β1 ADRB1 Rat Adrenoceptors A pKi 6.08 6.08 6.08 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 7.96 7.96 7.96 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 8.68 8.68 8.68 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.28 7.28 7.28 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.63 6.63 6.63 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.6 8.61 8.62 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 ChEMBL
D1 DRD1 Rat Dopamine A pKi 6.13 6.13 6.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database