CHEMBL270177


SMILES CC1NC(N)=Nc2cccc(Cl)c21
InChIKey XFMPGBXLGWZMQP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 195.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 8.29 8.29 8.3 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKd 8.5 8.51 8.52 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
H1 HRH1 Human Histamine A pKi 5.96 5.96 5.96 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.82 6.82 6.82 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.72 6.72 6.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database