CHEMBL270408


SMILES COc1ccccc1N1CCN(Cc2cccc(OCCF)c2)CC1
InChIKey FTRMVNZQPKCUAS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 344.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.28 5.28 5.28 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.8 8.8 8.8 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.57 6.57 6.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.24 7.24 7.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database