CHEMBL3104093
SMILES | CN1CCc2c(c3cccc4c3n2CCc2ccccc2-4)C1 |
InChIKey | XKGPHJMKJBEURD-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 2 |
Hydrogen bond donors | 0 |
Rotatable bonds | 0 |
Molecular weight (Da) | 288.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT1B | 5HT1B | Human | 5-Hydroxytryptamine | A | pKi | 5.91 | 5.91 | 5.91 | ChEMBL |
5-HT1D | 5HT1D | Human | 5-Hydroxytryptamine | A | pKi | 6.2 | 6.2 | 6.2 | ChEMBL |
α1B | ADA1B | Human | Adrenoceptors | A | pKi | 5.65 | 5.65 | 5.65 | ChEMBL |
α1D | ADA1D | Human | Adrenoceptors | A | pKi | 6.53 | 6.53 | 6.53 | ChEMBL |
α2B | ADA2B | Human | Adrenoceptors | A | pKi | 5.36 | 5.36 | 5.36 | ChEMBL |
α2C | ADA2C | Human | Adrenoceptors | A | pKi | 6.35 | 6.35 | 6.35 | ChEMBL |
H2 | HRH2 | Human | Histamine | A | pKi | 6.03 | 6.03 | 6.03 | ChEMBL |
5-HT7 | 5HT7R | Human | 5-Hydroxytryptamine | A | pKi | 6.71 | 6.71 | 6.71 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 5.86 | 5.88 | 5.91 | ChEMBL |
α1A | ADA1A | Human | Adrenoceptors | A | pKi | 6.54 | 6.54 | 6.54 | ChEMBL |
α2A | ADA2A | Human | Adrenoceptors | A | pKi | 6.39 | 6.39 | 6.39 | ChEMBL |
5-HT2B | 5HT2B | Human | 5-Hydroxytryptamine | A | pKi | 6.98 | 6.98 | 6.98 | ChEMBL |
5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 6.59 | 6.59 | 6.59 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |