T-226296
| SMILES | CN(CC1CCc2c(C1)ccc(c2)NC(=O)c1ccc(cc1)c1ccc(cc1)F)C |
| InChIKey | GXAQELJVODWLDD-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 2 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 5 |
| Molecular weight (Da) | 402.2 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| MCH1 | MCHR1 | Human | Melanin-concentrating hormone | A | pKi | 7.42 | 7.84 | 8.26 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| MCH1 | MCHR1 | Human | Melanin-concentrating hormone | A | pIC50 | 8.3 | 8.3 | 8.3 | Guide to Pharmacology |
| MCH1 | MCHR1 | Human | Melanin-concentrating hormone | A | pIC50 | 6.06 | 7.68 | 8.26 | ChEMBL |
| MCH1 | MCHR1 | Rat | Melanin-concentrating hormone | A | pIC50 | 7.62 | 7.62 | 7.62 | ChEMBL |