CHEMBL27559


SMILES CCCN1CCc2cccc3c2[C@H]1Cc1cccc(O)c1-3
InChIKey WZJSIHGOLMMBAL-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 279.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.96 6.19 6.36 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.85 7.74 9.05 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.4 7.4 7.4 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.37 6.36 7.35 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.77 7.34 8.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.94 6.94 6.94 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.35 7.35 7.35 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.94 7.42 7.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database