CHEMBL316961


SMILES N[C@@H](c1cccc(C(F)(F)F)c1)[C@@H]1CCN1C(c1ccccc1)c1ccccc1
InChIKey GAEAFMJGLPCGOT-VXKWHMMOSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 396.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 6.63 7.07 7.51 ChEMBL
δ OPRD Human Opioid A pKi 4.96 5.09 5.22 ChEMBL
μ OPRM Human Opioid A pKi 5.22 5.46 5.71 ChEMBL
κ OPRK Human Opioid A pKi 5.45 5.62 5.79 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database