UCM 549


SMILES COc1ccc2c(c1)C(CNC(=O)C)Cc1c(C2)cccc1
InChIKey PQZZGTZTKGECDT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT1 MTR1A Human Melatonin A pKi 7.6 7.9 8.2 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 8.9 9.05 9.2 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 8.89 9.08 9.18 ChEMBL
MT1 MTR1A Human Melatonin A pKi 7.57 8.0 8.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database