CHEMBL287587


SMILES NCC(O)c1ccc(O)c(O)c1F
InChIKey FOTRTWXNJQSQJS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 2
Molecular weight (Da) 187.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Rat Adrenoceptors A pKi 5.82 5.82 5.82 ChEMBL
β2 ADRB2 Dog Adrenoceptors A pKi 6.85 6.85 6.85 ChEMBL
β1 ADRB1 Rat Adrenoceptors A pKi 5.6 6.14 6.68 ChEMBL
β1 B0FL73 Guinea pig Adrenoceptors A pKi 6.46 6.46 6.46 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 5.0 5.0 5.0 PDSP Ki database
α1B ADA1B Human Adrenoceptors A pKi 5.4 5.4 5.4 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 B0FL73 Guinea pig Adrenoceptors A pEC50 6.52 6.52 6.52 ChEMBL
α1A ADA1A Human Adrenoceptors A pEC50 4.15 4.15 4.15 ChEMBL