CHEMBL293225


SMILES COc1ccc(Br)cc1-c1nc(CNC2CCN(Cc3ccccc3)CC2)co1
InChIKey MLHOXJCQVSTIML-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 455.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.9 4.9 4.9 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.41 6.41 6.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.24 6.24 6.24 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.03 6.12 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database