CHEMBL295186


SMILES c1ccc(C[C@H]2C3CCC(C3)[C@H]2NC2=NCCO2)cc1
InChIKey NUMRIDYCRYHYHT-SSHXOBKSSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 270.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 7.39 7.39 7.39 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.1 7.1 7.1 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.86 7.86 7.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 7.86 7.86 7.86 ChEMBL