CHEMBL301039


SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC(C1)N2C
InChIKey HTMNINCXKXABOI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 323.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Rat 5-Hydroxytryptamine A pKi 7.31 7.31 7.32 ChEMBL
H3 HRH3 Rat Histamine A pKi 9.5 9.5 9.5 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pKi 7.32 7.32 7.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pEC50 5.95 6.66 7.14 ChEMBL