CHEMBL3040115


SMILES CN1CCc2ccc(Cc3ccccc3)c3c2[C@H]1Cc1ccc(O)c(O)c1-3
InChIKey PNZJHNPWNQIJPQ-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 357.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.78 6.78 6.78 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.26 7.26 7.26 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.11 7.11 7.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pEC50 7.11 7.11 7.11 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.31 7.31 7.31 ChEMBL