CHEMBL3040157


SMILES CN(C)c1ccc(Cc2ccc3c4c2-c2c(ccc(O)c2O)C[C@H]4N(C)CC3)cc1
InChIKey YPEMPEGPBFGRNH-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 400.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.87 6.87 6.87 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.28 7.28 7.28 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.1 7.1 7.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pEC50 6.13 6.13 6.13 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.76 6.76 6.76 ChEMBL