CHEMBL308480


SMILES O=C1CC(CN2CCC(C(=O)c3ccc(F)cc3)CC2)Cc2ccccc21
InChIKey JFVJCLYJXOVMSI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 7.2 7.2 7.2 ChEMBL
D1 DRD1 Rat Dopamine A pKi 6.49 6.49 6.49 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.68 7.68 7.68 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.11 6.34 6.63 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.63 8.27 8.8 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.47 6.7 6.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database