CHEMBL3087214


SMILES COC(=O)N1[C@H]2CC[C@@H]1C[C@@](O)(C#Cc1cccc(F)c1)C2
InChIKey BWMLEHOGRQOGBL-QLPKVWCKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 303.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.11 7.11 7.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.17 7.17 7.17 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.21 7.21 7.21 ChEMBL