CHEMBL3087514


SMILES COC(=O)N1C[C@@H]2[C@@H](CCC2(O)C#Cc2cccc(C)c2)C1
InChIKey CIZDIEPYKQXGQG-SWQDIRLTSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 299.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 6.96 6.96 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 6.73 6.92 7.11 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 6.99 7.06 7.13 ChEMBL