BROTIZOLAM


SMILES Cc1nnc2n1-c1sc(Br)cc1C(c1ccccc1Cl)=NC2
InChIKey UMSGKTJDUHERQW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 392.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pKi 7.09 7.42 7.76 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pIC50 6.52 6.52 6.52 ChEMBL
PAF PTAFR Human Platelet-activating factor A pIC50 8.19 8.19 8.19 Drug Central