CHEMBL3262542


SMILES O=C1Cc2ccccc2N1C1CCN([C@H]2CC[C@@H]3CCCc4cccc2c43)CC1
InChIKey SZKWDIATUVLAAW-CYFREDJKSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.68 8.68 8.68 ChEMBL
κ OPRK Human Opioid A pKi 6.29 6.29 6.29 ChEMBL
μ OPRM Human Opioid A pKi 7.38 7.38 7.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.07 7.07 7.07 ChEMBL
μ OPRM Human Opioid A pEC50 6.39 6.39 6.39 ChEMBL