CHEMBL325253


SMILES O=C(CCCN1CCN(CC2CC(=O)c3ccsc3C2)CC1)c1ccc(F)cc1
InChIKey LGAZBHZJAUYBTQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 5.6 5.6 5.6 ChEMBL
D1 DRD1 Rat Dopamine A pKi 5.87 5.87 5.87 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.4 5.4 5.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database