CHEMBL310310


SMILES CN1C2CCC1CC(OC(c1ccccc1)c1ccc(Cl)cc1)C2
InChIKey OCAXFDULERPAJM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 341.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 7.06 7.25 7.44 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 8.1 8.44 8.83 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.27 5.27 5.27 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.76 5.76 5.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPS NPSR1 Human Neuropeptide S A Potency 6.5 6.5 6.5 ChEMBL