CHEMBL3309518


SMILES O=C1CCC2=C([C@@H]3Oc4c(O)ccc5c4[C@@]34CCN(CC3CC3)[C@H](C5)[C@]4(O)C2)N1CC1CCCCC1
InChIKey PORHWQUNKOJZAB-UJLGHMMASA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 490.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 6.06 6.06 6.06 ChEMBL
δ OPRD Human Opioid A pKi 9.55 9.55 9.55 ChEMBL
κ OPRK Human Opioid A pKi 9.48 9.48 9.48 ChEMBL
μ OPRM Human Opioid A pKi 9.96 9.96 9.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database