CHEMBL3314850


SMILES O=C(Nc1cncc(Oc2cncnc2)n1)c1cc(Cl)ccn1
InChIKey UEUUWJVQGWZIJY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 328.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.43 7.43 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.2 7.21 7.21 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.07 7.07 7.07 ChEMBL