DIFLUOROBENZTROPINE


SMILES CN1C2CCC1CC(OC(c1ccc(F)cc1)c1ccc(F)cc1)C2
InChIKey MHNSOBBJZCWUGS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 343.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 7.31 7.31 7.31 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 7.94 7.99 8.21 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.94 7.94 7.94 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.84 6.84 6.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database