corticotrophin-releasing hormone
| SMILES | None |
| InChIKey | None |
| Sequence | SEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Endogenous/Surrogate | Endogenous |
| Approved drug | No |
Database connections
| Ligand site mutations | CRF1 |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pKd | 7.1 | 8.05 | 9.0 | Guide to Pharmacology |
| CRF2 | CRFR2 | Mouse | Corticotropin-releasing factor | B1 | pKi | 7.8 | 7.8 | 7.8 | Guide to Pharmacology |
| CRF2 | CRFR2 | Rat | Corticotropin-releasing factor | B1 | pKd | 7.9 | 7.9 | 7.9 | Guide to Pharmacology |
| CRF2 | CRFR2 | Human | Corticotropin-releasing factor | B1 | pKd | 6.5 | 6.95 | 7.4 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |