CHEMBL3358503


SMILES COc1cccc(N2CCN(CCCCNC(=O)c3ccc4ccccc4n3)CC2)c1
InChIKey KAXPLEDCXIAJCF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 418.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.81 6.81 6.81 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.51 7.51 7.51 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.16 7.16 7.16 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.58 7.58 7.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database