CHEMBL323176


SMILES C/C(=N\OCC(O)CNC(C)(C)C)c1cc(Cl)c(NC2=NCCN2)c(Cl)c1
InChIKey DFLDWAZRXNATBE-OPEKNORGSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 7
Molecular weight (Da) 415.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 B0FL73 Guinea pig Adrenoceptors A pKd 4.3 4.38 4.6 ChEMBL
β2 ADRB2 Guinea pig Adrenoceptors A pKd 4.0 4.03 4.1 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 4.9 5.13 5.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database