CHEMBL3233143


SMILES O=C(CCCN1CC[C@H]2[C@@H](C1)c1cccc3c1N2CCN3)c1ccc(F)cc1
InChIKey WPJSNLWFVMFFSG-FPOVZHCZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 379.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 7.52 7.52 7.52 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.96 6.96 6.96 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.55 6.55 6.55 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.03 9.03 9.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database