CHEMBL3237905


SMILES C[C@H](c1ccc(C(=O)NCCC(=O)O)cc1)N1C(=O)C(c2ccc(F)c(Cl)c2)=N[C@]12CC[C@@H](C(C)(C)C)CC2
InChIKey XSFDICUHIRJKNV-YQWIOWDRSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 555.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
glucagon GLR Human Glucagon B1 pIC50 6.36 6.86 7.36 ChEMBL
GLP-1 GLP1R Human Glucagon B1 pIC50 5.37 5.37 5.37 ChEMBL
glucagon GLR Mouse Glucagon B1 pIC50 5.64 5.64 5.64 ChEMBL