CHEMBL326454


SMILES CNc1cc(OC)c(C(=O)N[C@H]2CN(Cc3ccccc3)C[C@H]2C)cc1Cl
InChIKey DCJWAUUNGWWIFD-KUHUBIRLSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 387.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.33 5.36 5.39 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.08 9.36 9.64 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.0 7.87 8.74 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.43 8.57 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database