CHEMBL1182151


SMILES COc1cccc(-c2ccccc2)c1OCCNC[C@H]1COc2ccccc2O1
InChIKey JVQZYMVBXVUIPJ-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 8.99 8.99 8.99 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 8.12 8.12 8.12 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.75 7.75 7.75 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 8.21 8.21 8.21 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.92 8.92 8.92 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.16 8.16 8.16 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.47 8.47 8.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database