CHEMBL328246


SMILES CC(C)=C1c2ccc(Cl)cc2C=C(N2CCN(C)CC2)c2ccccc21
InChIKey QCJIDMPIJUWNKR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 364.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 7.01 7.01 7.01 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.03 6.03 6.03 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.16 6.16 6.16 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.43 6.43 6.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 6.35 6.35 6.35 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 5.3 5.3 5.3 ChEMBL