CHEMBL3287395


SMILES CCOC(=O)c1cc2cc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)ccn2n1
InChIKey HXHZPLKJASKRCI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 490.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.82 6.82 6.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.13 8.15 8.17 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.68 8.68 8.68 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.33 7.33 7.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 6.36 6.36 6.36 ChEMBL
D3 DRD3 Human Dopamine A pEC50 7.24 7.25 7.25 ChEMBL