CHEMBL328866


SMILES COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C1
InChIKey CPVZPPFHQBIJNB-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 427.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 5.14 5.14 5.14 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 5.27 5.27 5.27 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.66 6.66 6.66 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.68 8.68 8.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database