CHEMBL3289647


SMILES Cc1ccc(N2CCN(CCCSc3ccc(F)cc3)CC2)nc1
InChIKey FLNJSRMYQSEHEU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 345.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.7 7.71 7.71 ChEMBL
D5 DRD5 Human Dopamine A pKi 5.67 5.69 5.7 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.65 6.65 6.65 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.96 5.98 6.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.77 6.79 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database