CHEMBL3290014


SMILES O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cc2ccc(Cl)cc2s1
InChIKey ZMIWRRKLVCCVBJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 521.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.48 8.48 8.48 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.89 8.89 8.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.92 8.92 8.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database