CHEMBL3290576


SMILES CN1CCN(c2nc(N)nc(-c3ccc(Cl)cc3)n2)CC1
InChIKey WWJYDYWCKUZUPY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 304.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.57 5.57 5.57 ChEMBL
H3 HRH3 Human Histamine A pKi 4.88 4.88 4.88 ChEMBL
H4 HRH4 Human Histamine A pKi 6.69 6.69 6.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pIC50 6.29 6.29 6.29 ChEMBL