CHEMBL3290578


SMILES CN1CCN(c2nc(N)nc(-c3ccc(Br)cc3)n2)CC1
InChIKey AOUFPRQIPFCXPL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 348.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.28 6.28 6.28 ChEMBL
H3 HRH3 Human Histamine A pKi 4.82 4.82 4.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pIC50 5.79 5.79 5.79 ChEMBL