CHEMBL105762


SMILES C[C@@H]1CC[C@@H](C)N1CCCOc1ccc(-c2ccc(C#N)cc2)cc1
InChIKey QJFIAPPKZLXTPP-QZTJIDSGSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 334.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.19 8.19 8.19 ChEMBL
H1 HRH1 Human Histamine A pKi 6.25 6.25 6.25 ChEMBL
H3 HRH3 Human Histamine A pKi 9.17 9.17 9.17 ChEMBL
H2 HRH2 Human Histamine A pKi 5.04 5.04 5.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database