CHEMBL3298692


SMILES CC(C)(C)OC(=O)NCCOc1ccc(Nc2ccc(CCNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)cc2)cc1
InChIKey ABNDMYBELMAXRP-NDEPHWFRSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 6
Rotatable bonds 12
Molecular weight (Da) 574.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Human Adrenoceptors A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β3 ADRB3 Human Adrenoceptors A pEC50 7.9 7.9 7.9 ChEMBL
β1 ADRB1 Human Adrenoceptors A pEC50 7.9 7.9 7.9 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 8.6 8.95 9.3 ChEMBL