CHEMBL330171


SMILES CCn1ncc(-c2ccc3c(c2)c(C2CCN(CCN4CCNC4=O)CC2)cn3-c2ccc(F)cc2)n1
InChIKey NEBSYJAENXRLFM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 501.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.68 6.68 6.68 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.43 7.43 7.43 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.07 7.07 7.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database