CHEMBL330603


SMILES Cn1nnnc1-c1ccc2c(c1)c(C1CCN(CCN3CCNC3=O)CC1)cn2-c1ccc(F)cc1
InChIKey KZPAEJGLSCXYBV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 488.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.29 7.29 7.29 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database