CHEMBL354210


SMILES O=C(NCCN1CCN(C2CCCc3ccccc32)CC1)c1ccccc1
InChIKey GFORNYWGPFXWHV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 363.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 7.16 7.34 7.52 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 4.66 4.66 4.66 ChEMBL
D2 DRD2 Bovine Dopamine A pKi 6.89 6.92 6.96 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.96 9.18 9.4 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 7.44 7.64 7.85 ChEMBL